Category: Mobile Phase Suggestions
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10mM Ammonium Acetate Buffer 90:10 in Acetonitrile Preparation for HPLC and LCMS - Tips & Suggestions
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Ammonium Fluoride Affect On Chromatography Using Cogent TYPE-C HPLC Columns - Tech Information
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Avoid Spurious Peaks from Nylon Syringe Filters with DI Water Using Electrochemical Detection - Tips & Suggestions
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Back Pressure That is Lower than Normal Using a Cogent Diamond Hydride HPLC Column - Tech Information
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Buffer Concentration can Affect ANP Retention of Acids in HPLC Analyses - Tips and Suggestions
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Choose a Suitable Mobile Phase Additive for Negative Ionization Mode in LCMS - Tips & Suggestions
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Cocaine and Polar Metabolites ( Ecgonine) Separation using LC‑MS / MS - Tips and Suggestions
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Considerations for keeping gases dissolved in solution when using sparging stones - Tips & Suggestions
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For Sugars Analyzed by LCMS Sodium Acetate is recommended for Sensitivity of Na Adducts - Tips & Suggestions
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How to handle sparging stones to avoid contamination of mobile phases - Tips & Suggestions
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If an analyte is only soluble at basic pH can you use a basic mobile phase for my method - FAQ
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Is TFA or formic acid better as an acidic mobile phase additive for Cogent TYPE-C columns - FAQ
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LCMS Challenges with HILIC Mobile Phases from Salt Buildup and Ion Suppression Explained - Tips & Suggestions
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My retention times are changing after storing my buffer and what could be causing this and tips to help avoid issues - FAQ
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Phosphoric Acid and Sodium Phosphate Use with Cogent Diamond Hydride Columns - Tech Information
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Positive or Negative ion mode Salt Suggestions for LC-MS Method Development - Tips & Sugeestions
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Prepare a 16mM Ammonium Acetate Buffer 90:10 in Acetonitrile for HPLC - Tips & Suggestions
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Restoring the Initial Method Results Analyzing AMP ADP ATP UDP and GPT in Biological Extracts - Troubleshooting
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Simple Sugars Methods using Triethylamine TEA in Aqueous Normal Phase ANP Methods - Tips & Suggestions
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Suggestion for separation of phenylephrine HCl acetaminophen and dextromethorphan - Tips & Suggestions
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To obtain greater sensitivity than Na adducts for sugars could you add ammonia NH4 instead - FAQ
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Type of gradient to use for analysis of hydrophilic and hydrophobic molecules in the same HPLC or LCMS run - Tips & Suggestions
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Using methanol instead of acetonitrile in an HPLC method should be done with caution - Tips & Suggestions
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What is the durability of the SOLVFIL when used with standard mobile phases and buffered mobile phases - FAQ
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What is the maximum salt concentration to use with Cogent TYPE-C HPLC columns with HPLC or LCMS - FAQ
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